AMSA P-D en es it fr

AMSA P-D Brand names, AMSA P-D Analogs

AMSA P-D Brand Names Mixture

  • No information avaliable

AMSA P-D Chemical_Formula

C21H19N3O3S

AMSA P-D RX_link

No information avaliable

AMSA P-D fda sheet

AMSA P-D msds (material safety sheet)

AMSA_P-D MSDS

AMSA P-D Synthesis Reference

No information avaliable

AMSA P-D Molecular Weight

393.46 g/mol

AMSA P-D Melting Point

234-236oC

AMSA P-D H2O Solubility

<1 mg/mL

AMSA P-D State

Solid

AMSA P-D LogP

5.273

AMSA P-D Dosage Forms

Liquid

AMSA P-D Indication

For treatment of acute myeloid leukaemia.

AMSA P-D Pharmacology

Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.

AMSA P-D Absorption

Poorly absorbed

AMSA P-D side effects and Toxicity

Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).

AMSA P-D Patient Information

No information avaliable

AMSA P-D Organisms Affected

Humans and other mammals