2-Methyl-3-phythyl-1,4-naphthochinon
Category
2-Methyl-3-phythyl-1,4-naphthochinon Brand names, 2-Methyl-3-phythyl-1,4-naphthochinon Analogs
2-Methyl-3-phythyl-1,4-naphthochinon Brand Names Mixture
No information avaliable
2-Methyl-3-phythyl-1,4-naphthochinon Chemical_Formula
C31H46O2
2-Methyl-3-phythyl-1,4-naphthochinon RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
2-Methyl-3-phythyl-1,4-naphthochinon fda sheet
2-Methyl-3-phythyl-1,4-naphthochinon msds (material safety sheet)
2-Methyl-3-phythyl-1,4-naphthochinon Synthesis Reference
No information avaliable
2-Methyl-3-phythyl-1,4-naphthochinon Molecular Weight
450.696 g/mol
2-Methyl-3-phythyl-1,4-naphthochinon Melting Point
-20 oC
2-Methyl-3-phythyl-1,4-naphthochinon H2O Solubility
Insoluble in water
2-Methyl-3-phythyl-1,4-naphthochinon State
Liquid
2-Methyl-3-phythyl-1,4-naphthochinon LogP
8.841
2-Methyl-3-phythyl-1,4-naphthochinon Dosage Forms
Liquid
2-Methyl-3-phythyl-1,4-naphthochinon Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
2-Methyl-3-phythyl-1,4-naphthochinon Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
2-Methyl-3-phythyl-1,4-naphthochinon Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
2-Methyl-3-phythyl-1,4-naphthochinon Toxicity
No information avaliable
2-Methyl-3-phythyl-1,4-naphthochinon Patient Information
No information avaliable
2-Methyl-3-phythyl-1,4-naphthochinon Organisms Affected
Humans and other mammals