1,4-Naphthoquinone,_2-methyl-3-phytyl-

Category

1,4-Naphthoquinone,_2-methyl-3-phytyl-




Useful info

1,4-Naphthoquinone,_2-methyl-3-phytyl- Brand names, 1,4-Naphthoquinone,_2-methyl-3-phytyl- Analogs

1,4-Naphthoquinone,_2-methyl-3-phytyl- Brand Names Mixture

  • No information avaliable
  • 1,4-Naphthoquinone,_2-methyl-3-phytyl- Chemical_Formula

    C31H46O2

    1,4-Naphthoquinone,_2-methyl-3-phytyl- RX_link

    http://www.rxlist.com/cgi/generic3/phytonadione.htm

    1,4-Naphthoquinone,_2-methyl-3-phytyl- fda sheet

    1,4-Naphthoquinone,_2-methyl-3-phytyl- msds (material safety sheet)

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Synthesis Reference

    No information avaliable

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Molecular Weight

    450.696 g/mol

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Melting Point

    -20 oC

    1,4-Naphthoquinone,_2-methyl-3-phytyl- H2O Solubility

    Insoluble in water

    1,4-Naphthoquinone,_2-methyl-3-phytyl- State

    Liquid

    1,4-Naphthoquinone,_2-methyl-3-phytyl- LogP

    8.841

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Dosage Forms

    Liquid

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Indication

    For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Pharmacology

    Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Absorption

    Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Toxicity

    No information avaliable

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Patient Information

    No information avaliable

    1,4-Naphthoquinone,_2-methyl-3-phytyl- Organisms Affected

    Humans and other mammals